The Champions League group stage has hit its midpoint, with each team having played three games. The usual suspects (Real Madrid, Bayern Munich, Chelsea) have a place in the knockout stage nearly secured, but a number of European giants are in danger of crashing out of the competition by December.

Manchester City

Ivan Sekretarev/AP

Manchester City has been crowned champion of England twice in the past three seasons, but City has only ever gone as far as the Round of the 16 in the Champions League. In 2014, Manchester City was drawn in the group of death alongside Bayern Munich and Roma, and City only managed a single point from those two games to start the group — meaning the club desperately needed a win against CSKA Moscow. In a cold, empty stadium Tuesday, CSKA shocked City with a late penalty earn a 2-2 draw, leaving City on two points, seven points behind Bayern and two points behind Roma.

Manchester City still has home games against Bayern and CSKA, along with a road trip to Italy to play Roma, and if City will need at least two wins from those three games to have a good chance of going through. Roma controls its own destiny, and it isn’t likely that City will take points off of Bayern, which just trounced Roma 7-1.

Liverpool

Pierre-Philippe Marcou/AFP

Perhaps selling the best player on the team wasn’t the best idea after all? Suarez-less Liverpool hasn’t looked like the team that finished second in the Premier League last season, and Cristiano Ronaldo’s Real Madrid handed Liverpool a comprehensive 3-0 defeat Wednesday.

Liverpool has a favorable schedule for the second half of the group stage, with Basel and Ludogorets Razgrad coming to Anfield — two teams that Liverpool should beat comfortably. No team is a pushover, though. Basel beat Liverpool 1-0 in Switzerland, and Razgrad has been competitive in one-goal losses to Real Madrid and the Reds.

Juventus

Aris Messinis/AFP

Despite rampaging through the Serie A season last year in Italy, winning the title by an absurd 17 points over Roma, Juventus failed to make it out of the group stages in the Champions League. This year, Juventus is once again atop the Serie A table and has yet to lose a game in the league, but sits in third in Group A after three games, behind Atlético Madrid and Olympiacos.

Group A has proven to be completely unpredictable. Juventus was likely the favorite to win the group after the draw, but lost 1-0 in Greece to Olympiacos Tuesday, after losing 1-0 to Atlético in Spain. Olympiacos has wins over Juve and Atlético, but lost to massive underdog Malmö from Sweden.

Olympiacos and Atlético are tied at the top of the group with six points, three more than Juventus in third — but the Italian club has the benefit of two home matches and just one away. The December 9th showdown between Atlético and Juventus in Turin on the final day of the group could likely end up being a win-or-face elimination game.